Johne's disease or Mycobacterium Paratuberculosis usually creeps into a herd through the purchase of infected cattle, even 10 years prior to an out break. It decreases milk production from 5% to 25% according to a study by the National Health Monitoring System (NAHS) entitled "Johne's Disease on US Dairy Operations." This loss can and does take place even though the cardinal signs of diarrhea and weight loss are not apparent.
Recently field studies using Karbo Flour have demonstrated an ability to reverse the effects of Johne's on the bowel of the bovine animals with diarrhea, establish normal stools and begin to gain weight and increase production.
Johne's positive cows treated at least twice at 3 week intervals have not reverted back to the diarrhea stage, but have gained weight and appear thrifty. One draw back is that we do not have a test for Johne's that is much more than 50% accurate in diagnosing the disease. Therefore, at this point in time it is not known if the Johne's organism is eliminated completely or merely set back in its development within the host animal.